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By directly modifying drugs that have already gained clinical approval, this approach substantially cuts down the time required for drug development, offering a route to enhance drug effectiveness and mitigate side effects

The study supports the concept that GHSs may provide a safer and more physiologic alternative to exogenous GH therapy by stimulating endogenous pulsatile GH release, thereby avoiding supraphysiologic IGF-1 levels [2]

Proposed mechanisms for its development include disintegration and aggregation of lens proteins, glutathione deficiency, damage to fiber cell membranes, oxidative stress, increased calcium levels, in addition to abnormal migration of lens epithelial cells [16]

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These natural compounds found in breast milk, along with antioxidants such as glutathione (GSH), superoxide dismutase (SOD), and lactoferrin, contribute to newborns' robust antioxidant capacity

Cells were lysed by probe sonication using a Branson Sonifer 250 ultrasonic cell disruptor (2 12 pulses, 10% power output)