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As described earlier, central to the pathogenesis of alopecia areata is loss of immune privilege of the hair follicle, which can have a connection between both autoimmune and apoptotic pathways, and exposure to stress factors plays a central role in most of the cases associated with increased risk of both initiation or recurrence of the disease

Cyanogenic glycosides can be lethal if there is excessive consumption by the intended consumers

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I B kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal

FIGURE 2 TABLE 2 A summary of some inducers and inhibitors of ferroptosis

The first and rate-limiting step is catalyzed by the enzyme glutamate-cysteine ligase (GCL), which fuses glutamate and cysteine