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CrossRef G Protein-Coupled Estrogen Receptor-1 Is Involved in the Protective Effect of Protocatechuic Aldehyde against Endothelial Dysfunction Byung Soo Kong, Yoon Hee Cho, Eun Jig Lee, Rajesh Mohanraj PLoS ONE.2014

Thus, NM plays a dual roleprotective in healthy neurons and potentially harmful when degraded or released extracellularly (266270)

Limited Human Reports A small number of human publications exist, but their scale and design do not establish general safety or effectiveness

Challenges in linking preclinical anti-microbial research strategies with clinical outcomes for device-associated infections

Studies discovered mitochondrial-derived peptide called MOTS-c has been shown to significantly reduce the level of pro-inflammatory factors in mice and increase anti-inflammatory factors and insulin-stimulated glucose treatment rates, as well as glucose homeostasis (79)

doi: 10.2217/fvl.13.58 2 AllenM