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: Neutrophil chemotaxis in granulomatosis with polyangiitis (Wegeners) and idiopathic pulmonary fibrosis

PTMs of GPX4 affect the protein level/activity of GPX4, indicating that modifying these processes can be a potential therapy for treating ferroptosis-related diseases

PUFA: Polyunsaturated fatty acid

Matsuo T, Okura N, Kakuda H, Yano Y

Dispersed islet cells from high-fat diet (HFD)-fed hIAPP Tg/0 and hIAPP 0/0 littermates on an F1 C57BL/6J FVB/NJ background were pooled (five mice per sample) and sorted into CD45 + and CD45 fractions via BD FACS ARIA II (BD Biosciences), and reconstituted to a final composition of 30% CD45 cells and 70% CD45 + cells

Excess activation of the glutamate receptors, specifically NMDA receptors, causes excitotoxicity from too much neuronal stimulation.[ref] Substances that act on glutamate receptors: This is just hitting the highlights and isnt exhaustive