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Anti-Inflammatory Effects & Mucosal Protection Chronic inflammation underlies many GI conditions, from Crohns disease to IBS

(1) Microglia become overwhelmed and cannot keep up with demand, and/or (2) shift into a less sensitive state trying to keep inflammatory signals to a minimum by reducing their reactivity to endogenous ligands (Hickman et al., 2013)

Intriguingly, fasting has emerged as an attractive anti-cancer strategy through mechanisms involving the AMPK/AKT/GSK3 axis 7

Statistical significance was determined using two-tailed Students t test through GraphPad Prism5 software unless otherwise mentioned

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