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In the mitochondria, the DNA glycosylase, OGG1 (mt-OGG1), can deoxidize ox-mtDNA, thereby maintaining mtDNA quality

CD8+ T cells and neutrophils promote cancer cell ferroptosis by secreting interferon (IFN-) and transferring myeloperoxidase-containing particles, followed by the release of immunostimulatory signals from ferroptotic cancer cells, which promotes the maturation of dendritic cells (DCs), the activation of M1-polarized macrophages, and the enhancement of intratumoral T-cell infiltration and activity (10)

Indeed, increased NOX activity has been linked with AD progression and individuals converting from cognitively intact to dementia status (148)

The IL-33/ST2 axis in immune responses against parasitic disease: potential therapeutic applications

The tubes were centrifuged at 48,000 g for 18 h at 4 C using a Hitachi CP100WX centrifuge with a P40ST rotor

Inflammation, aging, oxidative stress, and hypoxia are the most important mechanisms that can explain the relationship between these pathologies