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It allows continued monitoring of the benefit/risk balance of the medicinal product

It also alters melanin production from eumelanin (dark pigment) to phaeomelanin (lighter pigment), which contributes to its skin-brightening effect.(2) This mechanism explains why its often promoted as a depigmenting agent for issues like melasma, sun spots, and post-inflammatory hyperpigmentation

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ACC, Anterior Cingulate Cortex