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Separately, intranasal administration of Lactobacillus casei CRL 431 has been shown to enhance the immune response to Streptococcus pneumoniae infection, as evidenced by increased levels of interleukin-10 (IL-10), interleukin-4 (IL-4), IgA, and TNF-in the respiratory tract (252)

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10.1016/j.ijbiomac.2024.130522 41 HirakuraK.MoritaM.NakajimaK.SugamaK.TakagiK.NiitsuK.et al (1997)