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Ethics declarations Competing Interests The authors declare no competing interests

Eur J Hum Genet

The following sections detail how compromised AT propagates dysfunction through altered adipokine secretion, excessive free fatty acid release, inflammatory mediator production, and EV signaling, establishing self-perpetuating cycles that progressively worsen whole-body metabolic homeostasis

Kim J, Thomas SN

The impact of these regulatory RNAs extends to metabolic tissues including pancreatic -cells, hepatocytes, and skeletal muscle (291)

Especially after the occurrence of COVID-19, a number of studies related to oxidative stress have been conducted, but they tend to be limited to inflammation and immunity only, ignoring the possible additional links with the older population, who are the most infected with CAP