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296,297,298,299 Importantly, in these in vivo studies, niclosamide have shown limited toxicity providing hopeful optimism for Wnt inhibition in human cancer therapy

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Source: Ahmadi S, Bashiri R, Ghadiri-Anari A, Nadjarzadeh A

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Although genetics is by far the most important factor, environmental influences, like infections during pregnancy and exposure to pollution, may also play a role