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Similarly, the neuroprotective agent baicalin has demonstrated potential in mitigating METH-induced amnesia and cognitive impairment in animal studies

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However, at the same time, iron overload interferes with the fusion of autophagosomes with lysosomes and inhibits lysosomal acidification and hydrolase activity, thereby blocking the autophagy process [67, 68] (Fig

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The top-ranked model, selected on discrete optimized protein energy (DOPE) scores 104 , was duplicated and arranged according to the C2 symmetry observed in the occluded ABCB7 structure to generate a full homodimeric assembly