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72-hour backward trajectories from in Soverato mainly originate from northern Africa and they are associated with substantial moisture transport (Figure S13), with a WVMR variability showing values larger than 6 g kg -1 in the trajectory origin (within one standard deviation, though the trajectory ensemble reports values up to ~ 12 g kg -1 )

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Mortality benefits correlated with normalization of multiple systems: Circadian melatonin rhythms restored Carbohydrate metabolism improved Lipid profiles normalized Immune function enhanced Animal studies demonstrated lifespan extension across multiple species, with epithalamin increasing mean lifespan up to 41% in rodent models [11]

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