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Mechanistic studies have established that Dihexas procognitive and synaptogenic effects are mediated by the hepatocyte growth factor (HGF) / c-Met receptor system rather than by the classical AT 4 receptor, despite Dihexas structural origin as an angiotensin IV derivative

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23 In the situation of a vertebral fracture (injury type A2) but intact disc/endplate complex and in the presence of sufficient bone quality, the involved trauma energy can by assumed to be much higher than in the aforementioned twin study from Hancock and Batti

The peptide also demonstrates protection against corticosteroid-induced tendon damage, which is particularly relevant for athletes who have received steroid injections

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