glutathione glycine units Induction of biosynthesis by glycine-based treatment mitigates atherosclerosis Glutathione-Mediated Conjugation of Anticancer Drugs:

Although hydrolysis of ester- and amide-containing drugs is sometimes included among the phase I reactions (in the older terminology), the biochemistry of hydrolysis is more closely related to conjugation than to oxidation/reduction

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Glutathione or GSH is an endogenous antioxidant amino acid necessary to fight free radicals and neutralize oxidative stress

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E-mail: [email protected] Date of Received: 28-12-2010 Date of Accepted: 06-06-2011 Available Online: 15-08-2011 Abstract The primary role of glutathione transferase is to defend an organism from toxicities through catalyzing the reaction of glutathione (GSH) with potentially toxic compounds or metabolites to their chemically and biologically inert conju-gates