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Prolonged systemic use can also cause hypothalamic-pituitary-adrenal (HPA) suppression or signs/symptoms of Cushings syndrome (marked by high cortisol levels)

Annals of Allergy, Asthma & Immunology, 81, 203-210

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As a result, surface expression of B2M and class I HLAs is reduced, helping the virus evade identification and clearance of infected cells by cytotoxic CD8+ T cells (138, 158, 159)