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This is accompanied by the upregulation of pathways that mediate antigen presentation [e.g., major histocompatibility complex (MHC) II], phagocytosis related pathways such as C3, C4 and FCGR4, CD86 (Lagraoui et al., 2012), pathways that promote pro-inflammatory cytokines (e.g., IL-10, IL-6, IL-2, IFN-, IL-1) and chemokines expression (e.g., CXCL4, CCL4, CCL2)

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When your metabolism is healthy, you: Maintain stable energy throughout the day Burn fat efficiently Have healthy blood sugar regulation Maintain ideal body composition Experience mental clarity and focus Recover well from exercise Sleep restfully Age gracefully When your metabolism is dysfunctional, you experience: Weight gain and trouble losing weight despite diet and exercise Insulin resistance and elevated blood sugar Chronic fatigue and low energy Brain fog and poor concentration Increased belly fat (visceral adiposity) Poor exercise recovery Increased inflammation Accelerated aging Metabolic dysfunction is the root cause of most chronic diseases , including type 2 diabetes, cardiovascular disease, fatty liver disease, Alzheimers disease, and many cancers

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