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Melanin is the brown pigment that determines the colour of our skin

For total protein extraction, tissues or cells were homogenized in ice-cold RIPA lysis buffer (containing 1% protease and phosphatase inhibitors) using a mechanical homogenizer

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Two conserved epigenetic regulators prevent healthy ageing

Recent evidence suggested the beneficial aspect of co-treatment by atorvastatin combined with tamoxifen via elevated expression of pro-apoptotic factors (such as Bax and cytochrome C) in melanoma B16F10 cells compared to groups treated by only with tamoxifen or atorvastatin [92]