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FLI was calculated using a mathematical equation based on triglyceride levels, body mass index (BMI), gamma-glutamyl transferase (GGT), and waist circumference, resulting in values ranging from 0 to 100

Interestingly, SFN has a unique ability in Nrf2 activation, which enhances the expression of heme oxygenase-1 (HO-1) and nicotinamide adenine dinucleotide phosphate quinone oxidoreductase 1 (NQO1) (59, 67), thereby protecting neurons from 6-hydroxydopamine (6-OHDA), methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (68), amyloid (A) (69), and pro-inflammatory cytokines (70, 71)