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Numerous investigations have revealed that disturbances in zinc homeostasis within the brain lead to aggregation and ultimately facilitate the formation of neurofibrillary tangles (NFTs) (An et al., 2005[7]

10.1080/09168451.2015.1020752 124 ParkE

Gut Microbiome and Inflammation: In the gut, Berberine modulates the microbial community and reduces permeability, thereby lessening the systemic inflammation often linked to metabolic disorders