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Y., Liu, H

revealed that individuals with elevated STAT4 and PD-L1 levels experienced reduced overall survival (OS) compared to those with lower STAT4 and PD-L1 levels, indicating the crucial role of the MET/STAT4/PD-L1 pathway in facilitating glioma immune evasion, which is associated with a less favorable outlook in primary glioma cases [67]

J Clin Invest (1986) 77(1):16

The difference is not just theoretical

While this is true, there are other causes and, additionally, varying shades of lack of therapeutic responsiveness which must be recognized in order to preserve the use of an effective or partially effective drug