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Cancer Cell 41 , 15511566 (2023)

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When administered in vivo , IGF-I also enhances the population of intrasplenic B cells through increased proliferation of mature cells[172, 173] together with an influence on antibody expression and class switching by plasma cells[174]

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It is prohibited at all times in an out of competition and is not eligible for the therapeutic use exemption because it has no approved therapeutic uses