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Importantly, N-terminal acetylation promoted phase separation and reduced the aggregation of FUS-LCD in vitro

Rhythm disturbances have also been reported in all lcFAODs except CPT1A deficiency, and can occur with, but also without, the presence of cardiomyopathy [20, 31]

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Rather than empirical trial-and-error, the reaction was optimized using Design of Experiments (Central Composite Design) to model the combined influence of temperature and catalyst loading on yield

Common adverse effects include mild gastrointestinal discomfort, such as diarrhea, bloating, and nausea, which are typically transient and reversible [429, 430]

Future prospects Although this study focuses on acetylation, it is essential to recognize that the complexity of cellular signaling networks relies on both the synergy and antagonism among multiple PTMs