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Except for ethanol and nicotine, for which certain distributions could be fitted to the data for the European countries, uniform probability distributions were chosen in all other cases as only minimum/maximum prevalence values for Europe in total were available

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In order to win regulatory approval, e-cigarette companies must demonstrate that a product would be "appropriate for the protection of the public health." That means that any health benefits such as helping traditional cigarette smokers transition to generally less-harmful vaping must outweigh the risks of bringing the new product to market

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The study found mice who vaped had increased levels of each of these lung damage markers: Vaping causes lung damage that can be measured by multiple different tests that detect changes to lung tissue and pulmonary response