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For the majority, these symptoms are mild, but as many as 25% of women report that these symptoms are moderate to severe

doi: 10.1016/j.freeradbiomed.2023.06.004 128 MohammadiSAl-HarrasiA

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LNPs are most commonly manufactured using the microfluidic mixing technology in which the four lipid components (in organic phase) are rapidly mixed with the RNA solution (in aqueous phase) in the microfluidic mixer to form the resultant LNPs via self-assembly (Figure 1)