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doi: 10.1016/j.jplph.2008.04.004

SLC7A11 is a superior determinant of APR-246 (Eprenetapopt) response thanTP53Mutation status

Abstract The interplay between microbes and cancer has garnered significant attention in life sciences

It is also reported to be closely involved in the pathology of multiple sclerosis and other inflammatory diseases in the CNS [237]

EM maps and models generated in this study, of CBS basal state (EMD-19735, PDB 8S5H, EMD-19736, PDB 8S5I, EMD-19737, PDB 8S5J, EMD-19738, PDB 8S5K), degraded CBS tetramer (EMD-19739, PDB 8S5L) and CBS + SAM activated state (EMD-19740, PDB 8S5M, EMD-19741, EMD-19742), have been deposited to the Electron Microscopy Data Bank (EMDB) and Protein Data Bank (PDB)

Thereby, it protects or decreases neuronal cells from A-induced apoptosis and cisplatin-induced neuronal injury in a dose-dependent manner (Jang et al., 2004