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"Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial"

This relatively small sample size may limit the general applicability of the research results and increase the possibility of selection bias

Discussion In this population representative study, we observed that those with deficient-low B 12 status had a 51 % increased likelihood of developing depressive symptoms over 4 years

Important note: it remains investigational and lacks FDA approval for human use

The pair sold Ladder to Openfit for an undisclosed amount in 2020 after reporting more than $4 million in sales for that year

Offered by manufacturers, these programs may help eligible patients get the medication at little or no cost