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Avoiding these errors improves outcomes and reduces unnecessary side effects

In the absence of PKR, intestinal epithelial cells show impaired survival and proliferation, which exacerbates intestinal inflammation (100)

2001;131(9 Suppl):2515S22S discussion 2523S2514S

Further, studies show that about 20 ~ 30% of patients with metastatic melanoma initially respond to immune checkpoint blockade treatment but eventually develop resistance and relapse after therapy (173, 174)