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Rapid correction of acidosis with sodium bicarbonate in patients with diabetic ketoacidosis may cause hypokalemia, paradoxical acidosis in cerebrospinal fluid (CSF) since carbon dioxide diffuses more rapidly into CSF than does bicarbonate, and lactic acidosis since increased pH increases hemoglobin-oxygen affinity which, when combined with erythrocyte 2,3-diphosphoglycerate (2,3-DPG) deficiency in these patients, results in peripheral tissue hypoxia

Preparing an auto-injector If youre using a pen delivery system for a subcutaneous injection, filling it with medication is slightly different from filling a syringe

Carbamazepine or oxcarbazepine may work well at first, but later the dose may become insufficient or side effects may limit further increase

Important caveat: B12 injections are most effective when you have deficiency or suboptimal levels

Key terms No blood or urgency and normal bowel function

Inserting the needle at too shallow an angle could prevent the injection from reaching the intended depth and penetrating the muscle