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For patients with persistent pruritus, GABA receptor modulators, opioid agonists/antagonists, and phototherapy can be employed (Dhand and Aminoff 2014)

HO-1 as an important regulator of oxidative stress and inflammation, also plays an important role in diabetic kidney apoptosis

None of the above peptides have gone through one

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Another critical consideration is the substantial pharmacokinetic limitations of curcumin, which are one of the core bottlenecks hindering its clinical translation

After cell detachment with 25% trypsin solution (v/v), cells were incubated with BD Binding Buffer (BD Biosciences, Franklin Lakes, NJ, United States) and then incubated with 5 L of annexin V and 5 L of PI in the dark for 20 min