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She also highlights the raft of molecules currently in development, including glucagon-based agents or triple agonists: It will be interesting to see how the field develops over the next couple of years, where were going to have a wealth of potential tools for us to use in the clinic. Key points: In REDEFINE 2, cagrilintide, an amylin analogue, was investigated in combination with the GLP-1 receptor agonist semaglutide due to its targeting appetite regulation in a complementary mechanism of action

Schuckelt R, et al

The nuclear region was identified in the DAPI (blue) channel and similarly added to the ROI manager

Okamoto A, Sumi C, Tanaka H, Kusunoki M, Iwai T, Nishi K, et al