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The COA covers identity by mass spec, purity by HPLC at 99% per peptide, water content by Karl Fischer, and endotoxin by LAL

In clinical trials (NCT01124006, NCT01158924, NCT00813813, and NCT01182337), intradiscal GDF-5 has been used to evaluate the safety, tolerability, and preliminary effectiveness in patients with early-stage lumbar disc degeneration