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Treatment & Results: After intratympanic PRP therapy , the patient reported: A 2030 % reduction in tinnitus intensity Improved hearing thresholds (10 dB+) in low-to-mid frequencies (500 Hz2000 Hz) Enhanced clarity and reduced need for high television volume Follow-up audiograms continue to show sustained improvements

49 Loss of podocytes remains a critical factor in glomerulosclerosis, a hallmark of DKD progression 41 (Fig

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114 KurokawaS.TakehashiM.TanakaH.MiharaH.KuriharaT.TanakaS.et al (2011)

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FDA drug approval is a full review process involving Phase IIII clinical trials, demonstrated safety and efficacy in humans, and post-market surveillance obligations