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However, several limitations exist in differentiating MSCs into Schwann-like cells, such as the requirement of special induction medium, the time-consuming process (usually taking 2 ~ 3 weeks in special induction conditions) [48], the variation in the induction efficiency, and the phenotypic instability of MSC-derived Schwann-like cells, etc

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2019;10 doi: 10.3389/fimmu.2019.01023

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