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Description

A primary care physician or internist can diagnose and treat pernicious anemia

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An exciting recent development has been the discovery of itaconate as an anti-inflammatory metabolite which inhibits the succinate-hypoxia-inducible factor-1 axis (Lampropoulou et al., 2016)

For UA conjugated metabolites, glucuronidation enhances the molecules hydrophilicity, promoting renal excretion, whereas sulfation may attenuate the biological activity of the UA monomer