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This work is published and licensed by Dove Medical Press Limited

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Intraperitoneal injection of 4-hydroxynonenal (4-HNE), a lipid peroxidation product, exacerbates colonic inflammation through activation of Toll-like receptor 4 signaling

However, NOX enzymes contain heme-binding histidine residues within the third and fifth transmembrane domains that can accept electrons before transferring them to oxygen on the opposite, exofacial or lumenal side of the membrane

Antibody-dependent enhancement of dengue virus infection in U937 cells requires cholesterol-rich membrane microdomains

In addition, studies on murine hepatic mitochondria have shown that DZN inhibits state III respiration, which is driven by glutamate and malate, substrates of complex I of the respiratory chain, as well as succinate, a substrate of complex II [10]