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Description

Na, M., Yang, X., Deng, Y., Yin, Z

526 ChenJSet al

Circulation 124 , 24332443 (2011)

Within the hepatic microenvironment, markedly reduced blood flow (up to 1,000-fold slower than peripheral circulation), and the specialized sinusoidal architecture promote prolonged nanoparticle residence and sustained interaction with immune cells (Fig