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Iron export through the transporter ferroportin 1 is modulated by the iron chaperone PCBP2

In addition, ERS inducers such as tunicamycin and thapsigargin increased NNMT expression in both AML12 hepatocytes and mice (Song et al

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Since APR-246 is metabolized to MQ, we reasoned that direct treatment of the cell lysate with APR-246 may not allow for this conversion

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The phase of these genes was shifted by about 4 or +4 hours and also presented a lower amplitude in cKOt mice than in control mice (Figure 1, C and D and Supplemental Figure 1C)