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The figure shows the precursors of L-methylmalonyl-CoA: Fatty acids and amino acids can be metabolized to propionyl-CoA, which is converted to D-methylmalonyl-CoA and then to L-methylmalonyl-CoA

Neural tube defects Neural tube defects (NTD) may result in anencephaly or spina bifida, which are often fatal congenital malformations of the central nervous system

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It may point to liver disease, blood disorders or an underlying cancer that has not yet been detected

Improved metabolism