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The APR-246 reagent used in the in vivo study was provided by APREA therapeutics (Solna, Sweden)

(2004) in SOD1 G86R mice found aberrations of energy metabolism such as reduction of adiposity, increased energy expenditure and lipolysis, and examined the effects of a high fat diet that consisted of regular chow supplemented with 21% (wt/wt) butter fat and 0.15% (wt/wt) cholesterol

Such metabolism can reduce repetitive behaviors of mice with ASD

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L-theanine, an amino acid found in green tea that is being evaluated for potential benefit for some stress related symptoms as well as for cognitive function, was also added to the Category 1list

Swire J, Fuchs S, Bundy JG, Leroi AM