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For patients with recurrent episodes, prophylactic therapy may be initiated, starting with H1-antihistamines and stepping-up as needed

Moreover, since recent studies have shown that the de- and remyelination extend as well the cellular composition seems to differ between white and gray matter MS lesions (Bo et al., 2003

Sonis ST (2004) The pathobiology of mucositis

Mean body clearance in adults is reported to be 0.23 (17%) mL/min/kg

And years later, it's still a staple in our regimens

Jeong S-H, Jang J-H, Cho H-Y, Lee Y-B (2021) Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate