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Update on diabetic nephropathy: core curriculum 2018

The use of P5091 or P22077, two USP7 inhibitors, display a strong senolytic activity in several models of senescence 31

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Biochem 87:585620 [DOI] [PubMed] [Google Scholar] 31.Intlekofer AM, Wang B, Liu H, Shah H, Carmona-Fontaine C, et al

Their success in healing skin, bone, cartilage, nerve, and cardiovascular structures underscores their broad therapeutic potential (As shown in Figure 4)