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In experimental models of colon carcinogenesis induced by DMH/DSS, these compounds have been observed to attenuate tumor burden and volume, inhibit cell proliferation, and induce apoptosis, with minimal toxicity

Digests were then cleaned-up by SPE and reconstituted as above

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Alcohol dehydrogenase (ADH) first converts ethanol to acetaldehyde, which is then further metabolized by aldehyde dehydrogenases (ALDH) to acetate [186]