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38 The release of lysosomal enzymes into the cytosol is dependent on the specific lysosomal enzyme cathepsin B

Deficiency leads to nerve damage (neuropathy), which presents as numbness, tingling, or weakness

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Patients should be encouraged to consume B12-rich foods, including: Meat, particularly liver and kidney Fish and shellfish Dairy products (milk, cheese, yoghurt) Eggs Fortified breakfast cereals and plant-based milk alternatives For patients following plant-based diets, fortified foods and supplementation become essential, as vitamin B12 is naturally found almost exclusively in animal products

A., Liu, A

10a), base (Fig