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Together, these findings identify the melatonin-NRF2-glutathione axis as a metabolic checkpoint regulating innate type 2 immunity and suggest that therapeutic targeting of redox metabolism may represent a strategy for modulating airway inflammation in allergic asthma

Probably yes

These statements do not imply or establish safety, efficacy, bioavailability, or appropriateness for administration outside of controlled laboratory settings

doi: 10.7860/JCDR/2014/10258.5292 4 BarcelouxD

Moreover, these drugs are often associated with side effects such as gastrointestinal distress, dizziness, and nausea, further limiting their long-term clinical utility ( 4.4 Socioeconomic burden and the need for cost-effective therapies Beyond its medical impact, AD imposes a substantial socioeconomic burden, affecting patients, caregivers, and healthcare systems

Clinical manifestation and classification of ulcerative colitis