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When LDL cholesterol becomes oxidized, it becomes far more atherogenic and dangerous

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Interestingly, serum levels of total protein, albumin, and bilirubin, as well as the hepatic activities of AST, ALT, ALP, and GGT where comparable with the vehicle-treated control (Table 4)

In the past decade, pachymic acid ( 30 ) from Poria cocos , escin ( 31 ), acetyl-11-keto- -boswellic acid ( 32 ) from the genus Boswellia , pristimerin ( 33 ) from Menispermum dauricum , oleanolic acid acetate ( 34 ) from Vigna angularis , deacetyl ganoderic acid ( 35 ) from Ganoderma lucidum , 3- O -acetylrubianol C ( 36 ) from Rubia philippinesis , and lancemaside ( 37 ) from Codonopsis lanceolata inhibited the IKK activity or regulated the phosphorylation of IKK [149-155]

Evidence is limited, but precaution is warranted for individuals on multiple medications

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