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The leaving group in the conjugation of JS-K is 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate, which rapidly decomposes into 4-ethoxycarbonylpiperazine and the projected two active molecules of NO 8

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Concurrently, siNotch1 and siNotch3 inhibited hypoxia-induced RASFC invasion and angiogenesis in vitro , whereas N1ICD and N3ICD overexpression promoted these processes (200)

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Therefore, ACTL6A might promote GC cells proliferation via reducing ROS levels

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The Autoimmune Diseases (Sixth Edition)

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