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Abstract: Paul, C., & Brady, D

After treatment, cells were incubated with MTT reagent (0.1 mg/mL in DMEM) for 2 h

The proposed mechanisms are multiple and interconnected, reflecting the broad biological footprint of copper-dependent biology in mammalian tissues

Under such metabolic stress conditions, supplies of L-cysteine for glutathione synthesis become limiting, so homocysteine is diverted from the transmethylation pathway forming methionine into the transsulfuration pathway forming cystathionine

Thomas M, Nicklee T, Hedley DW (1995) Differential effects of depleting agents on cytoplasmic and nuclear non-protein sulphydryls: a fluorescence image cytometry study