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Conversely, BCAAs can also exacerbate hepatic oxidative stress and hepatocyte apoptosis

In various mouse models, DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) was crucial for cell survival, and proteasome inhibitors can prevent endothelial cell apoptosis and reduce mortality, significantly aiding in endothelial protection (Wesley et al., 2024

Curr Pharm Des 17(31):34133417

In these cases, people might not need as much medication

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