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S6A), and re-expressed UBE2m WT or R169K (RK) to explore whether UBE2m R169 methylation is involved in regulating fatty acid metabolism in TECs

The pathophysiological mechanisms, including inducing autoimmune responses, hormonal disorders, and exerting an effect on the possible thyroid-gut-microbiome-brain axis, have underpinned the role of GD as a crucial driver in the development of depression and depressive symptoms

Asparagine is important in the removal of toxic ammonia from the body

The cysteine residue required for NCL was subsequently desulfurized to an alanine residue to yield the wildtype sequence (Fig

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