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Acta 1 , 1939 (2003)

The immune incompetence of huCD34 engrafted NSG mice limits the utility of direct immunization, however the protection afforded by transfer or repRNA-elicited IgG clearly highlights a key role of antibodies in anti-EBV immunity

L-GSH supplementation also increased the levels of Th1-associated cytokines, IFN-, TNF-, and IL-2 and decreased levels of IL-6 and IL-10

In PD, there is a loss of cholinergic neurons in the basal forebrain and a reduction in nicotinic receptor availability

Research suggests that the SARS-CoV-2 virus can directly hijack mitochondrial function during the acute infection phase, altering the mitochondrial membrane potential and downregulating the expression of key metabolic enzymes

Ferroptosis is an iron-dependent, lipid peroxidation-driven form of programmed cell death, the execution of which centers on the uncontrolled accumulation of PL-OOH (phospholipid hydroperoxides), and unlike the accidental necrosis caused by severe external insults, ferroptosis is a form of programmed cell death